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Product Name
Human GABARAP / Apg8p1 (His & MBP Tag) recombinant protein
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Description
Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
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Protein name
Gamma-aminobutyric acid receptor-associated protein
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Protein short names
GABA-A RECEPTOR-ASSOCIATED PROTEIN; ATG8A; GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN; GAMMA-AMINOBUTYRIC ACID RESEPTOR ASSOCIATED PROTEIN; GABARAP; HT004; GABARAP-A; MM46; GABA(A) RECEPTOR-ASSOCIATED PROTEIN; GAMMA-AMINOBUTYRIC ACID RECEPTOR ASSOCIATED PROTEIN; RP23-172M21.5
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Uniprot ID
Q6IAW1
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Gene Name
GABARAP; FLC3B; HT004
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human GABARAP (NP_009209.1) (Met1-Leu117) was expressed with an N-terminal polyhistidine-tagged MBP tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human GABARAP consists of 514 amino acids and predicts a molecular mass of 57.5 KDa. It migrates as an approximately 49-58 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human GABARAP / Apg8p1 Protein (His & MBP Tag) SDS-PAGE
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