FMRFamide 6 peptide

FMRFamide 6 peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

H-AAASDNFMRF-NH2

H-Ala-Ala-Ala-Ser-Asp-Asn-Phe-Met-Arg-Phe-NH2

10

95.77%

C₄₉H₇₃N₁₅O₁₄S

1128.26

Synthetic

Powder

Extended FMRFamides are found throughout the central nervous system (CNS) of insects and exhibit diverse physiological effects on different target organs, such as muscles, intestine, and the nervous system.
FMRFamide 6 is identified by gene cloning and sequencing from the thoracic ganglionic sheath of two strains of green bottle fly/Australian sheep blowfly (Lucilia cuprina), which are found in Australia and Bangladesh respectively. The number of 6 is in accordance with its position in the precursor.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• Rahman MM, Fromm B, Neupert S, Kreusch S, Predel R. Extended FMRFamides in dipteran insects: conservative expression in the neuroendocrine system is accompanied by rapid sequence evolution. Gen Comp Endocrinol. 2009;162(1):52-8.

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.