Human aFGF / FGF1 recombinant protein
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.
Fibroblast growth factor 1
Protein short names
FGF-1; aFGF; ECGF; HBGF-1
A DNA sequence encoding the mature form of human FGF acidic (AAA79245.1) (Phe 16-Asp 155) was expressed, with an additional Met at the N-terminus.
The recombinant human FGF acidic consists of 141 amino acids and has a calculated molecular mass of 16 kDa as estimated by SDS-PAGE under reducing conditions.
> 95 % as determined by SDS-PAGE
Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts.
The ED50 for this effect is typically 50-200 pg/ml.
Human aFGF / FGF1 Protein SDS-PAGE
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