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Product Name
Human aFGF / FGF1 recombinant protein
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Description
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.
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Protein name
Fibroblast growth factor 1
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Protein short names
FGF-1; aFGF; ECGF; HBGF-1
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Uniprot ID
P05230
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Gene Name
FGF1; FGFA
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human FGF acidic (AAA79245.1) (Phe 16-Asp 155) was expressed, with an additional Met at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human FGF acidic consists of 141 amino acids and has a calculated molecular mass of 16 kDa as estimated by SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured in a cell proliferation assay using BALB/c 3T3 mouse fibroblasts.
The ED50 for this effect is typically 50-200 pg/ml. -
Validations
Human aFGF / FGF1 Protein SDS-PAGE
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