Fertirelin peptide
Not For Human Use, Lab Use Only.
Cat.#: 319674
Special Price 179.0 USD
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Product Name
Fertirelin peptide
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Documents
Batch to batch variation of the purity
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Sequence Shortening
Pyr-HWSYGLRP-NHEt
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Sequence
Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-NHEt
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Length (aa)
8
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Peptide Purity (HPLC)
95.86%
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Molecular Formula
C55H76N16O12
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Molecular Weight
1153.29
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CAS No.
38234-21-8
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PubChem CID
188304
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Source
Synthetic
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Form
Powder
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Description
Fertirelin is a GnRH and LH-RH analogue; it also becomes the treatment choice for reversing cow follicular cysts. Fertirelin, an analog of GnRH 2.5 to 10 times more potent than native GnRH , has become the treatment of choice for reversing follicular cysts. Administration of high doses of Fertirelin is found to reduce superovulatory responses.
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Storage Guidelines
Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
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References
- Nariai K, Ishinazaka T, Suzuki K, Uchiyama H, Sato K, Asano R, Tsumagari S, Yukawa M, Kanayama K. Optimum dose of LH-RH analogue Fertirelin Acetate for the induction of superovulation in mice. Exp Anim. 2005 Jan;54(1):97-9. doi: 10.1538/expanim.54.97. PMID: 15725686.
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About TFA salt
Trifluoroacetic acid (TFA) has a significant impact on peptides due to its role in the peptide synthesis process.
TFA is essential for the protonation of peptides that lack basic amino acids such as Arginine (Arg), Histidine (His), and Lysine (Lys), or ones that have blocked N-termini. As a result, peptides often contain TFA salts in the final product.
TFA residues, when present in custom peptides, can cause unpredictable fluctuations in experimental data. At a nanomolar (nM) level, TFA can influence cell experiments, hindering cell growth at low concentrations (as low as 10 nM) and promoting it at higher doses (0.5–7.0 mM). It can also serve as an allosteric regulator on the GlyR of glycine receptors, thereby increasing receptor activity at lower glycine concentrations.
In an in vivo setting, TFA can trifluoroacetylate amino groups in proteins and phospholipids, inducing potentially unwanted antibody responses. Moreover, TFA can impact structure studies as it affects spectrum absorption.
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Molar Concentration Calculator
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Dilution Calculator
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Percent Concentration Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Related Products / Services
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"