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Product Name
Human RNF43 (Fc Tag) recombinant protein
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Protein name
E3 ubiquitin-protein ligase RNF43
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Protein short names
RNF43; 4732452J19RIK; RING FINGER PROTEIN 43; RNF124; RP23-449P23.1; URCC; E3 UBIQUITIN-PROTEIN LIGASE RNF43
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Uniprot ID
Q68DV7
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Gene Name
RNF43
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human RNF43 (NP_060233.3) (Met1-Tyr197) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human RNF43/Fc comprises 412 amino acids and has a predicted molecular mass of 45.8 kDa. The apparent molecular mass of the protein is approximately 52 kDa in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
1. Measured by its binding ability in a functional ELISA.
2. Immobilized human RSPO3-His (146) (Cat:503038) at 10 μg/mL (100 μL/well) can bind human RNF43-Fc. The EC50 of human RNF43-Fc is 0.01-0.03μg/mL. -
Validations
Human RNF43 Protein (Fc Tag) SDS-PAGE
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