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Product Name
E.coli trpA/b1260/JW1252 recombinant protein
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Description
Tryptophan synthase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from animals such as humans. Tryptophan synthase typically exists as an α-ββ-α complex.The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate: L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H2O.The beta subunits catalyze the irreversible condensation of indole and serine to form tryptophan in a pyridoxal phosphate (PLP) dependent reaction. Their assembly into a complex leads to structural changes in both subunits resulting in reciprocal activation.
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Protein name
tryptophan synthase, alpha subunit(trpA)
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Protein short names
b1260; JW1252
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Uniprot ID
P0A877
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the E.coli trpA/b1260/JW1252 Met1-Ser268 is expressed.
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Protein Species
E.coli
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Purity
>95% as determined by SDS-PAGE.
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Validations
E.coli trpA/b1260/JW1252 recombinant protein
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