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  • DSESSEEDRTKREEVD peptide

DSESSEEDRTKREEVD peptide

Not For Human Use, Lab Use Only.

Cat.#: 319868

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* Buy 1 get 1 free (?) What is TFA?

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Product Information

  • Product Name
    DSESSEEDRTKREEVD peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    DSESSEEDRTKREEVD
  • Sequence
    Asp-Ser-Glu-Ser-Ser-Glu-Glu-Asp-Arg-Thr-Lys-Arg-Glu-Glu-Val-Asp
  • Length (aa)
    16
  • Peptide Purity (HPLC)
    95.9%
  • Molecular Formula
    C73H119N23O37
  • Molecular Weight
    1910.879
  • Source
    Synthetic
  • Form
    Powder
  • Description

    The polypeptide DSESSEEDRTKREEVD is a designed biomimetic sequence. It was constructed by connecting the collagen-binding domain "DSESSEEDR" from dentin matrix protein-1 (DMP-1) to the hydrophilic C-terminal sequence "TKREEVD" from amelogenin. Experimental analysis demonstrates that this synthetic polypeptide exhibits specific binding affinity to demineralized dentin collagen matrices. Furthermore, in vitro mineralization assays show that the polypeptide can sequester calcium and phosphate ions from solution and initiate the nucleation and growth of hydroxyapatite crystals. These properties indicate its functional role in mimicking key aspects of natural biomineralization processes.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Liu W, Cao Y, Shen J, Xu Q, Zhu Z, Li Q. [Design and evaluation of a kind of biomimetic peptides of dentin matrix protein-1]. Hua Xi Kou Qiang Yi Xue Za Zhi. 2013 Aug;31(4):341-4. Chinese. PMID: 23991567.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"