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Product Name
Human DMP1 (His Tag) recombinant protein
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Description
May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite.
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Protein name
Dentin matrix acidic phosphoprotein 1
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Protein short names
DMP1; AV020965; DMP-1; DMP; ARHP; PP; MGC130441; ARHR
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Uniprot ID
Q13316
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Gene Name
DMP1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human DMP1 (Q13316-1) (Met 1-Tyr 513) was expressed, with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human DMP1 consists of 508 amino acids and predictes a molecular mass of 55.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhDMP1 is approximately 53 kDa.
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Purity
> 85 % as determined by SDS-PAGE
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Activity
Measured by its ability to bind human CFH in a functional ELISA.
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Validations
Human DMP1 Protein (His Tag) SDS-PAGE
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