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Product Name
Human DCUN1D2/DCN1-like protein 2 (His Tag)
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Description
Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
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Protein name
DCN1-like protein 2
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Protein short names
DOMAIN CONTAINING 2; RP11-102K13.4; DOMAIN CONTAINING 2 (S. CEREVISIAE); DCUN1 DOMAIN-CONTAINING PROTEIN 2; C13ORF17; DEFECTIVE IN CULLIN NEDDYLATION 1; DEFECTIVE IN CULLIN NEDDYLATION PROTEIN 1-LIKE PROTEIN 2; DCN1; DCN1-LIKE PROTEIN 2; MFLJ10704; AW495713; DCUN1D2
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Uniprot ID
Q6PH85
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Gene Name
DCUN1D2; C13orf17; DCUN1L2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human DCUN1D2 (NP_001014305.1) (Met1-Phe259) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human DCUN1D2 consists of 277 amino acids and predicts a molecular mass of 32.4 KDa. It migrates as an approximately 33 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human DCUN1D2 Protein (His Tag) SDS-PAGE
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