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Product Name
Human CD131/CSF2RB/IL3RB/IL5RB (His Tag) recombinant protein
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Description
High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
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Protein name
Cytokine receptor common subunit beta
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Protein short names
IL3RB; MGC130522; CSFGMRB; SMDP5; CSF2RB; AI848964; BC; IL3RB1; GM-CSF/IL-3/IL-5 RECEPTOR COMMON BETA-CHAIN; AIC2B; CD131; IL3R; CSF2RB1; CDW131; IL5RB
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Uniprot ID
Q6NSJ8
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Gene Name
CSF2RB; IL3RB; IL5RB
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain (Met 1-Trp 443) of human CSF2RB (NP_000386.1) expressed, fused with a polyhistidine-tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CSF2RB consists of 438 amino acids and has a predicted molecular mass of 50 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CSF2RB is approximately 50-55 kDa.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA.
1. Immobilized human CD131 at 10 μg/ml (100 μl/well) can bind biotinylated human EPOR/Fc with a linear range of 0.16-4 μg/ml.
2. Immobilized human CD131 at 10 μg/ml (100 μl/well) can bind human GMCSF with a linear range of 0.032-4 μg/ml. -
Validations
Human CD131 / CSF2RB / IL3RB / IL5RB Protein (His Tag) SDS-PAGE
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