Cysteine dioxygenase type 1 antibody

Cysteine dioxygenase type 1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Cysteine dioxygenase type 1 Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue, rat liver tissue. Positive IP detected in mouse liver tissue. Positive IHC detected in human pancreas cancer tissue, human liver cancer tissue, human placenta tissue. Observed molecular weight by Western-blot: 23 kDa

ELISA, WB, IHC, IP

Human, Mouse, Rat; other species not tested.

CDO antibody; CDO I antibody; CDO1 antibody; Cysteine dioxygenase type 1 antibody; cysteine dioxygenase antibody; type I antibody

Rabbit IgG

This antibody was obtained by immunization of Cysteine dioxygenase type 1 recombinant protein (Accession Number: NM_001801). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

CDO1(cysteine dioxygenase type 1) is also named as CDO and belongs to the cysteine dioxygenase family. It is an enzyme that adds molecular oxygen to the sulfur of cysteine, converting the thiol to a sulfinic acid known as cysteinesulfinic acid (3-sulfinoalanine) and CDO1 is one of the most highly regulated metabolic enzymes responding to diet(PMID:19011731). The expression of CDO can significantly decrease the level of intracellular cysteine and this reduction is also associated with a decrease in total glutathione levels(PMID:17327371). Cysteine dioxygenase (CDO) plays a critical role in the regulation of cellular cysteine concentration andmultiple forms of CDO (23 kDa, 25 kDa, and 68 kDa) have been claimed based upon separation and detection using SDS-PAGE/western blotting(PMID: 14752623).

• Geillinger KE, Rathmann D, Köhrle J, Fiamoncini J, Daniel H, Kipp AP. Hepatic metabolite profiles in mice with a suboptimal selenium status. The Journal of nutritional biochemistry. 25(9):914-22. 2014.