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Cynomolgus IL13 / ALRH recombinant protein

Cat.#: 503522

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Product Information

  • Product Name
    Cynomolgus IL13 / ALRH recombinant protein
  • Documents
  • Description
    Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.
  • Protein name
    IL13
  • Protein short names
    P600; BHR1; MGC116789; ALRH; MGC116786; IL-13; MGC116788
  • Uniprot ID
    Q0PW92
  • Gene Name
    IL13
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Cynomolgus (Macaca fascicularis) IL13 (ABG75889.1) (Met 1-Asn 132) precursor was expressed.
  • Protein Species
    Cynomolgus
  • Molecular weight
    The recombinant Cynomolgus IL13 consists of 112 amino acids and has a calculated molecular mass of 12.3 kDa as estimated by SDS-PAGE under reducing conditions.
  • Purity
    > 85 % as determined by SDS-PAGE
  • Activity
    Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 2-8 ng/mL.
  • Validations

    Cynomolgus IL13 / ALRH Protein SDS-PAGE

    Cynomolgus IL13 / ALRH Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"