Cynomolgus CD90/THY-1 (His Tag) recombinant protein

Cynomolgus CD90/THY-1 (His Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Mouse Thy-1 membrane glycoprotein, also known as Thy-1 antigen, CD90 and THY1, is a cell membrane protein which contains 1 Ig-like V-type (immunoglobulin-like) domain. It is a glycophosphatidylinositol-linked glycoprotein expressed on the surface of neurons, thymocytes, subsets of fibroblasts, endothelial cells, mesangial cells and some hematopoietic cells. It has been identified on a variety of stem cells and at varying levels in non-lymphoid tissues such as on fibroblasts, brain cells, and activated endothelial cells. Thy-1 is evolutionarily conserved, developmentally regulated, and often has dramatic effects on cell phenotype. Thy-1 is a 25-37 kDa glycosylphosphatidylinositol (GPI)-anchored protein involved in T cell activation, neurite outgrowth, apoptosis, tumor suppression, wound healing, and fibrosis. To mediate these diverse effects, Thy-1 participates in multiple signaling cascades. Thy-1 is an important regulator of cell-cell and cell-matrix interactions, with important roles in nerve regeneration, metastasis, inflammation, and fibrosis.

THY-1.2; FLJ33325; THY-1; CD90; THY1; THY1.1; CDW90; THY1.2; T25

Human Cells

A DNA sequence encoding the cynomolgus THY1 (Met1-Lys129) was expressed with a polyhistidine tag at the C-terminus.

Cynomolgus

The recombinant cynomolgus THY1 comprises 121 amino acids and has a calculated molecular mass of 13.9 KDa. The apparent molecular mass of it is approximately 27-32 KDa in SDS-PAGE under reducing conditions.

> 90 % as determined by SDS-PAGE