Cynomolgus CD81 / TAPA-1 (His Tag) recombinant protein

Cynomolgus CD81 / TAPA-1 (His Tag) recombinant protein

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CD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition.

S5.7; CD81 ANTIGEN; CVID6; TAPA-1; 26 KDA CELL SURFACE PROTEIN TAPA-1; CD81; TETRASPANIN-28; TARGET OF THE ANTIPROLIFERATIVE ANTIBODY 1; TSPAN-28; TAPA1; CD81 ANTIGEN (TARGET OF ANTIPROLIFERATIVE ANTIBODY 1); TSPAN28; CD81 MOLECULE

Human Cells

A DNA sequence encoding the cynomolgus CD81 (XP_005576958.1) (Lys116-Lys201) was expressed with a polyhistidine tag at the N-terminus. Cynomolgus and Rhesus CD81 sequences are identical.

Cynomolgus

The recombinant cynomolgus CD81 consists of 105 amino acids and predicts a molecular mass of 11.7 kDa.

> 90 % as determined by SDS-PAGE.