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  • Cyclosaplin peptide

Cyclosaplin peptide

Not For Human Use, Lab Use Only.

Cat.#: 310952

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* Buy 1 get 1 free (?) What is TFA?

Special Price 398.00 USD

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Product Information

  • Product Name
    Cyclosaplin peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    RLGDGCTR (cyclic)
  • Sequence
    Arg-Leu-Gly-Asp-Gly-Cys-Thr-Arg (cyclic)
  • Length (aa)
    8
  • Peptide Purity (HPLC)
    96.3%
  • Molecular Weight
    858.98
  • Source
    Synthetic
  • Form
    Powder
  • Description

    Cyclosaplin is a cyclic octapeptide isolated from somatic seedlings of Santalum album L. (sandalwood). It has a molecular mass of 858 Da and its amino acid sequence was determined as RLGDGCTR. The peptide is cyclic in nature, as confirmed by mass spectrometry and chromatographic analyses. Structural characterization through molecular modeling revealed a compact cyclic conformation with a net positive charge and specific hydrophobic properties.

    In scientific studies, cyclosaplin demonstrated significant biological activity in cellular assays. Molecular docking experiments indicated strong binding affinity towards epidermal growth factor receptor (EGFR) and procaspase 3. The peptide's structure features prominent glycine and arginine residues, contributing to its structural stability and functional characteristics. This cyclic octapeptide represents a novel bioactive molecule from sandalwood with distinct structural and interaction properties.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Mishra A, Gauri SS, Mukhopadhyay SK, Chatterjee S, Das SS, Mandal SM, Dey S. Identification and structural characterization of a new pro-apoptotic cyclic octapeptide cyclosaplin from somatic seedlings of Santalum album L. Peptides. 2014 Apr;54:148-58. doi: 10.1016/j.peptides.2014.01.023. Epub 2014 Feb 3. PMID: 24503375..
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"