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  • Cyclo(-Arg-Gly-Asp-D-Phe-Cys) peptide

Cyclo(-Arg-Gly-Asp-D-Phe-Cys) peptide

Not For Human Use, Lab Use Only.

Cat.#: 303458

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* Buy 1 get 1 free (?) What is TFA?

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Product Information

  • Product Name
    Cyclo(-Arg-Gly-Asp-D-Phe-Cys) peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    c(RGDfC)
  • Sequence
    Cyclo(-Arg-Gly-Asp-D-Phe-Cys)
  • Length (aa)
    5
  • Peptide Purity (HPLC)
    95.64%
  • Molecular Formula
    C24H34N8O7S
  • Molecular Weight
    578.65
  • CAS No.
    862772-11-0
  • PubChem CID
    11330668
  • Source
    Synthetic
  • Form
    Powder
  • Description
    A RGD tumor-targeting peptide, which binds to alphavβ3 receptors. c(RGDfC) can be easily conjugated to drugs as combretastatin or surfaces. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. c(RGDfC) can disrupt cell integrin interactions.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • C.R.Pattillo et al., Pharm. Res., 22, 1117 (2005)
    • R.Nallamothu et al., AAPS PharmSciTech, 7, E32 (2006)
    • O.Prante et al., Bioconjugate Chem., 18, 254 (2007)
    • M.D.Stachler et al., Mol. Ther., 16, 1467 (2008)
    • K.Marko et al., Bioconjugate Chem., 19, 1757 (2008)
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"