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Product Name
Human CDKL2 (His Tag) recombinant protein
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Description
Cyclin-dependent kinase-like 2 (Cdkl2) is a member of cdc2-related serine / threonine protein kinase family and it is found expressed in various brain regions, including the cerebral cortex, entorinal cortex, hippocampus, amygdala, and dorsal thalamus. The high expression in these brain regions suggests that Cdkl2 may have functions in congnition and emotion processes. Cdkl2 accumulates primarily in the cytoplasm, with lower levels in the nucleus.
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Protein name
Cyclin-dependent kinase-like 2
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Protein short names
KKIAMRE; 5330436L21RIK; KKM; MGC144031; CDKL2; AI505225; P56; MGC144032
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Uniprot ID
Q92772
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Gene Name
CDKL2
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CDKL2 (Q92772) (Met 1-His 493) was expressed, with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CDKL2 consists of 512 amino acids and has a calculated molecular mass of 58.3 kDa. It migrates as an approximately 63 kDa band in SDS-PAGE under reducing conditions as predicted.
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Purity
> 85 % as determined by SDS-PAGE
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Activity
Kinase activity untested
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Validations
Human CDKL2 Protein (His Tag) SDS-PAGE
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