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Product Name
Human CBFB / CBF-beta (His Tag) recombinant protein
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Description
CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBFB enhances DNA binding by RUNX1.
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Protein name
Core-binding factor subunit beta
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Protein short names
PEBPB2; CBFB; PEBP2-BETA; CORE-BINDING FACTOR; BETA SUBUNIT; BETA SUBUNIT; CORE-BINDING FACTOR SUBUNIT BETA; AI893578; PEA2; CORE BINDING FACTOR BETA; POLYOMAVIRUS ENHANCER-BINDING PROTEIN 2 BETA SUBUNIT; SL3/AKV CORE-BINDING FACTOR BETA SUBUNIT; POLYOMAVIRUS ENHANCER BINDING PROTEIN 2; CBF-BETA; SL3-3 ENHANCER FACTOR 1 SUBUNIT BETA; PEA2-BETA; PEBP2; SL3-3 ENHANCER FACTOR 1 BETA SUBUNIT; PEBP2B
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Uniprot ID
Q13951
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Gene Name
CBFB
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human CBFB (Q13951-1) (Met1-Pro182) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CBFB consists of 197 amino acids and predicts a molecular mass of 23.3 KDa. It migrates as an approximately 27 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human CBFB / CBF-beta Protein (His Tag) SDS-PAGE
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