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Product Name
Human CD21 (His Tag) recombinant protein
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Description
Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.
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Protein name
Complement receptor type 2
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Protein short names
SLEB9; CD21; CR1; CVID7; RP11-78B10.1; CR-1; MGC130295; CD35; CR2; CR-2; C3DR; CR
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Uniprot ID
P20023
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Gene Name
CR2; C3DR
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CD21 isoform A (P20023-1) extracellular domain (Met 1-Arg 971) was expressed, with a carboxy-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The secreted recombinant human CD21 pro form consists of 962 amino acids with the predicted molecular mass of 106 kDa. As a result of glycosylation, the apparent molecular mass of rhCD21 is approximately 110-120 kDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA. Immobilized human CD21 at 2 μg/ml (100 μl/well) can bind biotinylated human CD9. The EC50 of biotinylated human CD9 is 1.76 μg/ml.
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Validations
Human CD21 / CR2 / C3DR Protein (His Tag) SDS-PAGE
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