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Product Name
Rat CLP1 / COLEC12 (His Tag) recombinant protein
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Description
Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR) (By similarity).
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Protein name
Collectin-12
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Protein short names
COLLECTIN-12; SCAVENGER RECEPTOR CLASS A; SCAVENGER RECEPTOR WITH C-TYPE LECTIN; NSR2; MEMBER 4; CLP1; COLLECTIN PLACENTA PROTEIN 1; SRCL; CL-P1; NURSE CELL SCAVENGER RECEPTOR 2; HCL-P1; SCARA4
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Uniprot ID
Q4V885
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Gene Name
Colec12; Clp1; Nsr2
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of rat COLEC12 (Q4V885) (Ala101-Leu742) was expressed,with a polyhistide tag at the N-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant ratCOLEC12 consists of 658 amino acids and predicts a molecular mass of 72.4 KDa. It migrates as an approximately 90 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 99 % as determined by SDS-PAGE
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Validations
Rat CLP1 / COLEC12 Protein (His Tag) SDS-PAGE
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