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Product Name
Human Cochlin (short isoform, His Tag) recombinant protein
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Description
Plays a role in the control of cell shape and motility in the trabecular meshwork.
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Protein name
Cochlin
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Protein short names
COCH-5B2; UNQ257/PRO294; DFNA9; COCH5B2; D12H14S564E; COCHLIN; COCH; AW122937
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Uniprot ID
O43405
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Gene Name
COCH; COCH5B2; UNQ257/PRO294
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human COCH (NP_001128530.1) (Glu 25-Gln 550) was expressed, with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant full length of human COCH consists of 542 amino acids and has a calculated molecular mass of 59.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCOCH is approximately 18 kDa, corresponding to the alternative splicing short isoform, whivch lacks two VWFA domains.
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Purity
> 92 % as determined by SDS-PAGE
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Validations
Human Cochlin / COCH Protein (short isoform, His Tag) SDS-PAGE
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