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Human Coagulation Factor XI/F11 (His Tag) recombinant protein

Cat.#: 500710

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Special Price 621.5 USD

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Product Information

  • Product Name
    Human Coagulation Factor XI/F11 (His Tag) recombinant protein
  • Documents
  • Description
    Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
  • Protein name
    Coagulation factor XI
  • Protein short names
    AI503996; PTA; CF11; COAGULATION FACTOR XI; FXI; MGC141891; 1600027G01RIK; F11
  • Uniprot ID
    P03951
  • Gene Name
    F11
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human F11 (NP_000119.1) precursor (Met 1-Val 625) with a carboxy-terminal polyhistidine tag was expressed.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human F11 consists of 618 amino acids with the predicted molecular mass of 69.5 kDa. As a result of glycosylation, rhCTSS migrates as an approximately 75-80 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 85 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to cleave the fluorogenic peptide substrate, t-butyloxycarbonyl-Ile-Glu-Gly-Arg-7-amido-4-methylcoumarin (Boc-IEGR-AMC). The specific activity is >100 pmoles/min/μg.
  • Validations

    Human Coagulation Factor XI / FXI / F11 Protein (His Tag) SDS-PAGE

    Human Coagulation Factor XI / FXI / F11 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"