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Product Name
Human Coagulation Factor IX / FIX / F9 (His Tag) recombinant protein
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Description
Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
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Protein name
Coagulation factor IX
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Protein short names
COAGULATION FACTOR IX; HEMB; CF-9; RP23-419J18.1; P19; FIX; RP6-88D7.1; F9; MGC129642; THPH8; CF9; AW111646; MGC129641; PTC
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Uniprot ID
P00740
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Gene Name
F9
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human F9 (AAB59620.1) (Met 1-Thr 461) was expressed, fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The secreted recombinant human F9 (pro form) consists of 444 amino acids and predictes a molecular mass of 50 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh F9 is approximately 60-80 kDa due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured by its ability to cleave the peptide substrate, Z-D-Arg-Gly-Arg-pNA. The specific activity is >20pmols/min/ug.
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Validations
Human Coagulation Factor IX / FIX / F9 Protein (His Tag) SDS-PAGE
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