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Product Name
Human CNTFR (His Tag) recombinant protein
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Description
Binds to CNTF. The alpha subunit provides the receptor specificity.
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Protein name
Ciliary neurotrophic factor receptor subunit alpha
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Protein short names
CNTFR-ALPHA; CNTFRALPHA; RP11-296L22.1; RATTUS NORVEGICUS; CNTF RECEPTOR SUBUNIT ALPHA; CNTFR ALPHA; CILIARY NEUROTROPHIC FACTOR RECEPTOR SUBUNIT ALPHA; CILIARY NEUROTROPHIC FACTOR RECEPTOR ALPHA
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Uniprot ID
P26992
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Gene Name
CNTFR
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
The amino acids sequence corresponding to (Met 1-Pro 346) of human CNTFR (NP_001833.1) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CNTFR consists of 335 amino acids and predicts a molecular mass of 36 kDa. The apparent molecular mass of rhCNTFR is approximately 45-48 kDa in SDS-PAGE under reducing conditions.
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Purity
> 98 % as determined by SDS-PAGE
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Activity
Measured by its binding ability in a functional ELISA. Immobilized human CTNFR at 10 μg/ml (100 μl/well) can bind biotinylated human CNTF with a linear ranger of 1.28-160 ng/ml.
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Validations
Human CNTFR / CNTFR-alpha Protein (His Tag) SDS-PAGE
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