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  • Chktide peptide

Chktide peptide

Not For Human Use, Lab Use Only.

Cat.#: 300843

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* Buy 1 get 1 free (?) What is TFA?

Special Price 291.00 USD

Availability: 3 weeks
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Product Information

  • Product Name
    Chktide peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    KKKVSRSGLYRSPSMPENLNRPR
  • Sequence
    Lys-Lys-Lys-Val-Ser-Arg-Ser-Gly-Leu-Tyr-Arg-Ser-Pro-Ser-Met-Pro-Glu-Asn-Leu-Asn-Arg-Pro-Arg
  • Length (aa)
    23
  • Peptide Purity (HPLC)
    98.2%
  • Molecular Formula
    C115H198N40O33S
  • Molecular Weight
    2701.17
  • CAS No.
    289652-77-3
  • Source
    Synthetic
  • Form
    Powder
  • Description
    CHKtide is a synthetic peptide substrate derived from CDC25C. CHKtide is a substrate for CHK1 and CHK2. Chktide can be used in kinase assays.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Walker M, Black EJ, Oehler V, Gillespie DA, Scott MT. Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity. Oncogene. 2009 Jun 18;28(24):2314-23. doi: 10.1038/onc.2009.102. Epub 2009 May 4. PMID: 19421147; PMCID: PMC2857325.
    • Bjørling-Poulsen M, Siehler S, Wiesmüller L, Meek D, Niefind K, Issinger OG. The 'regulatory' beta-subunit of protein kinase CK2 negatively influences p53-mediated allosteric effects on Chk2 activation. Oncogene. 2005 Sep 8;24(40):6194-200. doi: 10.1038/sj.onc.1208762. PMID: 15940255.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"