Cavia porcellus CTLA4 (His tag) recombinant protein

Cavia porcellus CTLA4 (His tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.

cytotoxic T-lymphocyte associated protein 4(Ctla4)

H0VUB1

Yeast

A DNA sequence encoding the Cavia porcellus CTLA4 Ala37-Asp161 is expressed with a 6His tag at the C-terminus.

Cavia porcellus

>95% as determined by SDS-PAGE.