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Product Name
Mouse Cathepsin B/CTSB (His Tag) recombinant protein
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Description
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
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Protein name
Cathepsin B
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Protein short names
CATHEPSIN B; APPS; CTSB; CATHEPSIN B1; CB; CPSB
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Uniprot ID
P10605
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Gene Name
Ctsb
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse CTSB (P10605) (Met 1-Phe 339) was fused with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse CTSB (pro form) consists of 333 amino acids and has a predicted molecular mass of 36.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm CTSB is approximately 35-43 kDa due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured by its ability to cleave the fluorogenic peptide substrate Z-LR-AMC (R&D Systems, Catalog # ES008). The specific activity is >2,000 pmoles/min/μg.
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Validations
Mouse Cathepsin B / CTSB Protein (His Tag) SDS-PAGE
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