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Product Name
Human CEACAM3/CD66d (His Tag) recombinant protein
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Description
Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.
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Protein name
Carcinoembryonic antigen-related cell adhesion molecule 3
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Protein short names
MGC119875; CEA12; W264; CEA; CEACAM3; PSG24; CGM1; EG384557; CD66D; W282
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Uniprot ID
P40198
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Gene Name
CEACAM3; CD66D; CGM1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CEACAM3 (NP_001806.2) extracellular domain (Met 1-Gly 155) was expressed, with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CEACAM3 consists of 132 amino acids and predictes a molecular mass of 14.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhCEACAM3 is approximately 18-23 kDa due to glycosylation.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human CEACAM3 / CD66d Protein (His Tag) SDS-PAGE
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