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Product Name
Mouse CHST5 / GlcNAc6ST-3 (Fc Tag) recombinant protein
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Description
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures. May also have activity toward O-linked sugars of mucin-type acceptors.
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Protein name
Carbohydrate sulfotransferase 5
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Protein short names
AI173964; I-GLCNAC-6-ST; I-GLCNAC6ST; GST-4; GLCNAC6ST-3; GN6ST-3; HIGN6ST
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Uniprot ID
Q9QUP4
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Gene Name
Chst5; Gst4
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse Chst5 (NP_064334.1) (Ser27-Ser395) was expressed with the Fc region of human IgG1 at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse Chst5 consists 629 amino acids and predicts a molecular mass of 70.1 kDa.
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Purity
> 90 % as determined by SDS-PAGE.
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Validations
Mouse CHST5 / GlcNAc6ST-3 Protein (Fc Tag)
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