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Product Name
Human CHST11 / C4ST-1 (His Tag) recombinant protein
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Description
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
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Protein name
Carbohydrate sulfotransferase 11
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Protein short names
C4ST-1; C4S; CHONDROITIN 4-O-SULFOTRANSFERASE 1; HSA269537; CHONDROITIN 4-SULFOTRANSFERASE 1; 1110020P09RIK; C4ST1; CHONDROITIN 4; CARBOHYDRATE (CHONDROITIN 4) SULFOTRANSFERASE 11; CARBOHYDRATE SULFOTRANSFERASE 11; IGH/CHST11 FUSION; CHST11; C4ST; C4S-1
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Uniprot ID
Q9NPF2
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Gene Name
CHST11
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CHST11 (Q9NPF2-2) (Met36-Glu347) was expressed with a C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The secreted recombinant human CHST11 consists of 323 amino acids and predicts a molecular mass of 38.4 KDa. The apparent molecular mass of the protein is approximately 43 KDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human CHST11 / C4ST-1 Protein (His Tag) SDS-PAGE
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