Human CHST11 / C4ST-1 (His Tag) recombinant protein
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
Carbohydrate sulfotransferase 11
Protein short names
C4ST-1; C4S; CHONDROITIN 4-O-SULFOTRANSFERASE 1; HSA269537; CHONDROITIN 4-SULFOTRANSFERASE 1; 1110020P09RIK; C4ST1; CHONDROITIN 4; CARBOHYDRATE (CHONDROITIN 4) SULFOTRANSFERASE 11; CARBOHYDRATE SULFOTRANSFERASE 11; IGH/CHST11 FUSION; CHST11; C4ST; C4S-1
A DNA sequence encoding the human CHST11 (Q9NPF2-2) (Met36-Glu347) was expressed with a C-terminal polyhistidine tag.
The secreted recombinant human CHST11 consists of 323 amino acids and predicts a molecular mass of 38.4 KDa. The apparent molecular mass of the protein is approximately 43 KDa in SDS-PAGE under reducing conditions.
> 95 % as determined by SDS-PAGE
Human CHST11 / C4ST-1 Protein (His Tag) SDS-PAGE
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