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Human CAMKI/CAMK1 recombinant protein

Cat.#: 501348

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Product Information

  • Product Name
    Human CAMKI/CAMK1 recombinant protein
  • Documents
  • Description
    Calcium/calmodulin-dependent protein kinase or CaM kinases are serine/threonine-specific protein kinases that are primarily regulated by the Calcium/calmodulin complex. These kinases show a memory effect on activation. CaM kinases activity can outlast the intracellular calcium transient that is needed to activate it. In neurons, this property is important for the induction of synaptic plasticity. Pharmacological inhibition of CaM kinases II blocks the induction of long-term potentiation. Upon activation, CaM kinases II phosphorylates postsynaptic glutamate receptors and changes the electrical properties of the synapse.
  • Protein name
    Calcium/calmodulin-dependent protein kinase I, isoform CRA_a
  • Protein short names
    CAMKI-ALPHA; CAM-KI; CAMKIALPHA; CAMK1; MGC120318; D6ERTD263E; MGC120317; AI505105; CAMKI
  • Uniprot ID
    Q14012
  • Gene Name
    CAMK1; hCG_21548
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human CAMK1 (NP_003647.1) (Leu 2-Leu 370) was expressed and purified, with two additional amino acids (Gly & Pro) at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human CAMK1 comprises 371 amino acids and has a predicted molecular mass of 41.5 kDa. The apparent molecular mass of the protein is approximately 42 kDa in SDS-PAGE under reducing conditions as predicted.
  • Purity
    > 85 % as determined by SDS-PAGE
  • Validations

    Human CAMK1 / CaMKI-alpha Protein SDS-PAGE

    Human CAMK1 / CaMKI-alpha Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"