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Product Name
Recombinant BOLA3 protein (His tag)
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Description
Recombinant BolA-like protein 3 (BOLA3) fragment (amino acids 1-107), a stable and soluble unit derived from human mitochondria, designed for structural and biochemical studies of iron-sulfur cluster assembly mechanisms.
BolA-like protein 3 is a mitochondrial iron-sulfur (Fe-S) cluster assembly factor in humans, facilitating Fe-S cluster insertion into specific mitochondrial proteins. It functions in coordination with NFU1 to support essential metabolic processes, with its localization strictly confined to the mitochondrion as confirmed by experimental evidence.
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Protein name
BolA-like protein 3
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Uniprot ID
Q53S33
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Gene Name
BOLA3
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-107 aa (Q53S33) were fused with C-terminal 6His tag.
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Sequence
MAAWSPAAAA PLLRGIRGLP LHHRMFATQT EGELRVTQIL KEKFPRATAI KVTDISGGCG AMYEIKIESE EFKEKRTVQQ HQMVNQALKE EIKEMHGLRI FTSVPKRLEH HHHHH
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 13.16 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 14 kDa band.
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Purity
>85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Validations
Recombinant BOLA3 protein (His tag) SDS-PAGE
M: Marker; Lane 1: BOLA3; Lane 2: BSA
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"