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Danio rerio (zebrafish) BMP-2 (zebrafish) recombinant protein

Cat.#: 501221

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Product Information

  • Product Name
    Danio rerio (zebrafish) BMP-2 (zebrafish) recombinant protein
  • Documents
  • Description
    BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.
  • Protein name
    Bmp2a protein
  • Protein short names
    BDA2A ; RP23-384M14.3; AI467020; BMP2A; BMP2; AI467020A; BDA2
  • Uniprot ID
    B3DI86
  • Gene Name
    bmp2a
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the zebrafish BMP2A (B3DI86) (Gln272-Arg386) was expressed and purified with an initial Met.
  • Protein Species
    Danio rerio (zebrafish)
  • Molecular weight
    The recombinant zebrafish BMP2A consists of 116 amino acids and has a calculated molecular mass of 13.2 kDa. It migrates as an 13 KDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells.
    The ED50 for this effect is typically 0.5-3 μg/mL.
  • Validations

    Danio rerio (zebrafish) BMP-2 / BMP2A Protein SDS-PAGE

    Danio rerio (zebrafish) BMP-2 / BMP2A Protein SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"