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  • BmKn2 peptide

BmKn2 peptide

Not For Human Use, Lab Use Only.

Cat.#: 307244

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* Buy 1 get 1 free (?) What is TFA?

Special Price 203.50 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    BmKn2 peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    FIGAIARLLSKIF
  • Sequence
    H-Phe-Ile-Gly-Ala-Ile-Ala-Arg-Leu-Leu-Ser-Lys-Ile-Phe-OH
  • Length (aa)
    13
  • Peptide Purity (HPLC)
    95.5%
  • Molecular Formula
    C71H117N17O15
  • Molecular Weight
    1447.8
  • Source
    Synthetic
  • Form
    Powder
  • Description

    BmKn2 is a cationic antimicrobial peptide derived from the venom of the scorpion Buthus martensii Karsch. Its primary sequence is FIGAIARLLSKIF. The peptide is characterized by an amphipathic α-helical structure, a net positive charge, and a significant proportion of hydrophobic amino acids. This conformational arrangement facilitates interactions with microbial membranes.

    Studies involving physicochemical modifications of the BmKn2 template, such as increasing net positive charge or altering terminal groups, have been conducted to investigate structure-activity relationships. These modifications influence properties like overall hydrophobicity, amphipathicity, and helical content, which in turn modulate the peptide's bioactivity profile in model systems.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Zeng XC, Wang SX, Zhu Y, Zhu SY, Li WX. Identification and functional characterization of novel scorpion venom peptides with no disulfide bridge from Buthus martensii Karsch. Peptides. 2004;25(2):143-50.
    • Mangmee S, Reamtong O, Kalambaheti T, Roytrakul S, Sonthayanon P. Antimicrobial Peptide Modifications against Clinically Isolated Antibiotic-Resistant Salmonella. Molecules. 2021 Jul 31;26(15):4654. doi: 10.3390/molecules26154654. PMID: 34361810; PMCID: PMC8348142.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"