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Product Name
Human BLOC1S2/BLOS2 (GST Tag) recombinant protein
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Description
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. May play a role in cell proliferation.
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Protein name
Biogenesis of lysosome-related organelles complex 1 subunit 2
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Protein short names
BLOC1S2A; BLOS2; BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2; CEAP11; RP11-316M21.4; CEAP; BLOC-1 SUBUNIT 2; CENTROSOME-ASSOCIATED PROTEIN; CENTROSOMAL 10 KDA PROTEIN; CENTROSOME PROTEIN ONCOGENE; 2410089B13RIK
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Uniprot ID
Q6QNY1
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Gene Name
BLOC1S2; BLOS2; CEAP
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human BLOC1S2 (Q6QNY1-2) (Met1-Arg99) was fused with the GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human BLOC1S2 /GST chimera consists of 333 amino acids and has a predicted molecular mass of 38.7 kDa. It migrates as an approximately 39 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 74 % as determined by SDS-PAGE
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Validations
Human BLOC1S2 / BLOS2 Protein (GST Tag) SDS-PAGE
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