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  • Atrial natriuretic peptide ANP (Polypterus endlicheri)

Atrial natriuretic peptide ANP (Polypterus endlicheri)

Not For Human Use, Lab Use Only.

Cat.#: 310879

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* Buy 1 get 1 free (?) What is TFA?

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Product Information

  • Product Name
    Atrial natriuretic peptide ANP (Polypterus endlicheri)
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    NSRGTSGCFGSRIDRIGSSSSLGCGGMKK-NH2
  • Sequence
    H-Asn-Ser-Arg-Gly-Thr-Ser-Gly-Cys-Phe-Gly-Ser-Arg-Ile-Asp-Arg-Ile-Gly-Ser-Ser-Ser-Ser-Leu-Gly-Cys-Gly-Gly-Met-Lys-Lys-NH2 (disulfide bond: Cys8-Cys24)
  • Length (aa)
    29
  • Peptide Purity (HPLC)
    95.9%
  • Molecular Formula
    C115H196N42O40S3
  • Molecular Weight
    2903.1
  • Source
    Synthetic
  • Form
    Powder
  • Description

    Atrial natriuretic peptide (ANP) from the bichir (Polypterus endlicheri), a primitive ray-finned fish, is a member of the natriuretic peptide family that plays a role in cardiovascular and fluid homeostasis in vertebrates.ANP mRNA is predominantly expressed in the atrium, with minor expression in the ventricle, consistent with its role as a cardiac hormone.The heart secretes ANP with natriuretic, diuretic, and vasodilatory activity.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Ventura A, Kawakoshi A, Inoue K, Takei Y. Multiple natriuretic peptides coexist in the most primitive extant ray-finned fish, bichir Polypterus endlicheri. Gen Comp Endocrinol. 2006;146(3):251-6.
    • Johnson KR, Olson KR. Comparative physiology of the piscine natriuretic peptide system. Gen Comp Endocrinol. 2008 May 15;157(1):21-6. doi: 10.1016/j.ygcen.2008.03.026. Epub 2008 Apr 7. PMID: 18472099.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"