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Product Name
Human ALOX5AP / 5-lipoxygenase-activating protein (His Tag)
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Description
Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.
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Protein name
Arachidonate 5-lipoxygenase-activating protein
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Protein short names
FLAP; ALOX5AP
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Uniprot ID
P20292
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Gene Name
ALOX5AP; FLAP
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the full length of human ALOX5AP (NP_001620.2) (Met 1-Pro 161) was fused with a polyhistidine tag at the carboxy-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human ALOX5AP consists of 167 amino acids and predicts a molecular mass of 19 kDa as estimated in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human ALOX5AP / FLAP Protein (His Tag) SDS-PAGE
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