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Product Name
Anti-MEKK2 Rabbit antibody
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Description
MEKK2 Rabbit polyclonal antibody
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Tested applications
WB, ICC/IF, FC, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
MEKK2; MEKK2B antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human MEKK2
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/2000-1/10000
ICC/IF: 1/50
FC: 1/20
IP: 1/20
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Validations
Immunocytochemistry of MEKK2(green) in Hela cells using MEKK2 Rabbit pAb at dilution 1/50, and DAPI(blue)
Western blot detection of MEKK2 in C6,3T3,Hela cell lysates using MEKK2 Rabbit pAb(1:1000 diluted).Predicted band size:70kDa.Observed band size:70kDa.
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Background
Swiss-Prot Acc.Q9Y2U5.Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 . Plays a role in caveolae kiss-and-run dynamics.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"