-
Product Name
Anti-MAP2K6 antibody
- Documents
-
Description
Rabbit Polyclonal to Human MAP2K6
-
Tested applications
IHC-P, ICC/IF, IF
-
Species reactivity
Human MKK6 / MEK6 / MAP2K6
-
Alternative names
MEK6 antibody; MKK6 antibody; MAPKK6 antibody; PRKMK6 antibody; SAPKK3 antibody; SAPKK-3 antibody; MEK6 antibody; MKK6 antibody; Prkmk6 antibody; SAPKK3 antibody; Map2k6 antibody; MAP2K6 antibody; MAPKK6 antibody; MEK6 antibody; MEK6 antibody; MKK6 antibody; MKK6 antibody; Prkmk6 antibody; PRKMK6 antibody; RP23-162E10.1 antibody; SAPKK3 antibody; SAPKK3 antibody
-
Isotype
Rabbit IgG
-
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human MKK6 / MEK6 / MAP2K6, and purified by antigen affinity chromatography.
-
Clonality
Polyclonal
-
Formulation
0.2 μm filtered solution in PBS
-
Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
IHC-P: 0.1-2 μg/mL
ICC/IF: 0.5-3 μg/mL
-
Validations
MKK6 / MEK6 / MAP2K6 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
MKK6 / MEK6 / MAP2K6 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
MKK6 / MEK6 / MAP2K6 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunofluorescence
-
Background
Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6 and MKK6, is a protein which belongs to the?protein kinase superfamily, STE Ser / Thr protein kinase family and MAP kinase kinase subfamily. MAP2K6 / MKK6 contains one?protein kinase domain. Mitogen-activated protein kinases are members of a conserved cascade of kinases involved in many signal transduction pathways. They stimulate phosphorylation of transcription factors in response to extracellular signals such as growth factors, cytokines, ultraviolet light, and stress-inducing agents. MAP2K6 / MKK6 exists in a variety of alternatively spliced isoforms with distinct patterns of tissue expression. Isoform 2 of MAP2K6 / MKK6 is only expressed in skeletal muscle. Isoform 1 of MAP2K6 / MKK6 is expressed in skeletal muscle, heart, and in lesser extent in liver or pancreas.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"