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Anti-KMT1E/SETDB1 (1E7) Mouse antibody

Cat.#: 168280

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-KMT1E/SETDB1 (1E7) Mouse antibody
  • Documents
  • Description
    KMT1E/SETDB1 (1E7) Mouse monoclonal antibody
  • Tested applications
    WB, ICC/IF
  • Species reactivity
    Human, Mouse, Monkey
  • Isotype
    Mouse IgG1
  • Preparation
    Antigen: Purified recombinant fragment of human SETDB1 expressed in E. Coli.
  • Clonality
    Monoclonal
  • Formulation
    Ascitic fluid containing 0.03% sodium azide.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/500 - 1/2000

    ICC: 1/200 - 1/1000

    ELISA: 1/10000

  • Validations

    Western blot detection of ESET in Jurkat,A549,MCF7 and C6 cell lysates using ESET mouse mAb (1:2000 diluted).Predicted band size:180KDa.Observed band size:180KDa.

    Western blot detection of ESET in Jurkat,A549,MCF7 and C6 cell lysates using ESET mouse mAb (1:2000 diluted).Predicted band size:180KDa.Observed band size:180KDa.

    Immunofluorescence analysis of LOVO cells using SETDB1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

    Immunofluorescence analysis of LOVO cells using SETDB1 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

  • Background
    Swiss-Prot Acc.Q15047.This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"