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Product Name
Anti-IgG4 Rabbit antibody
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Description
IgG4 Rabbit monoclonal antibody
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Tested applications
WB, IHC-P
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Species reactivity
Human
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthesized peptide derived from human IgG4
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Clonality
Monoclonal
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Formulation
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000-1/2000
IHC: 1/500-1/1000
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Validations
Western blot detection of IgG4 in HL-60,U2OS cell lysates using IgG4 Rabbit mAb(1:1000 diluted).Observed band size:36kDa.
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Background
Swiss-Prot Acc.P01861.IgG4 antibodies will dominate the IgG response in schistosomiasis, lymphatic filariasis, and in patients after allergen immunotherapy. Unlike the other IgG subclasses, IgG4 does not activate complement. A combined IgA-IgG4 deficiency has been associated with recurrent pyogenic infections.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"