Anti-GNG13 antibody

Anti-GNG13 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Human GNG13

ELISA, IHC-P

Human GNG13

AB030194 antibody; Ggamma13 antibody; 1500031D04Rik antibody; h2-35 antibody; G(gamma)13 antibody; 1500031D04Rik antibody; AB030194 antibody; clone 2-35 antibody; clone:h2-35 antibody; G gamma subunit antibody; G gamma subunit antibody; G(gamma)13 antibody; gamma antibody; gamma antibody; Ggamma13 antibody; guanine nucleotide binding protein 13 antibody; guanine nucleotide binding protein 13 antibody; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 antibody; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 antibody; h2-35 antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human GNG13 . GNG13 specific IgG was purified by Human GNG13 affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

GNG13 is a subunit of heterotrimeric G proteins which consist of alpha, beta, and gamma subunits. Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. They function as signal transducers for the 7-transmembrane-helix G protein-coupled receptors. They are involved as a modulator or transducer in various transmembrane signaling systems. Each G protein is composed of an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; in addition, some Gbetagamma subunits have active functions. Gbetagamma coupled to H1 receptors can activate PLA2 and Gbetagamma coupled to M1 receptors can activate KIR channels. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. GNG13 is a gamma subunit that is expressed in taste, retinal, and neuronal tissues and plays a key role in taste transduction.