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  • Anoplin peptide

Anoplin peptide

Not For Human Use, Lab Use Only.

Cat.#: 313333

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Product Information

  • Product Name
    Anoplin peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    GLLKRIKTLL
  • Sequence
    H-Gly-Leu-Leu-Lys-Arg-Ile-Lys-Thr-Leu-Leu-NH2
  • Length (aa)
    10
  • Peptide Purity (HPLC)
    97%
  • Molecular Formula
    C54H104N16O11
  • Molecular Weight
    1153.5
  • Source
    Synthetic
  • Form
    Powder
  • Description

    Anoplin is a novel antimicrobial peptide isolated from the venom of the solitary wasp Anoplius samariensis. It is a linear decapeptide with the amino acid sequence Gly-Leu-Leu-Lys-Arg-Ile-Lys-Thr-Leu-Leu-NH2. The peptide exhibits a high sequence homology to other amphipathic α-helical peptides, such as mastoparan-X and crabrolin, found in social wasp venoms.

    Structural analyses, including circular dichroism spectroscopy and molecular modeling, indicate that anoplin can adopt an amphipathic α-helical conformation in appropriate environments, such as in the presence of membrane-mimetic agents like sodium dodecyl sulfate or trifluoroethanol. In this conformation, its hydrophobic and cationic residues segregate to opposite faces of the helix. This peptide is noted for being one of the smallest linear α-helical antimicrobial peptides identified in nature.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Konno K, Hisada M, Fontana R, Lorenzi CC, Naoki H, Itagaki Y, Miwa A, Kawai N, Nakata Y, Yasuhara T, Ruggiero Neto J, de Azevedo WF Jr, Palma MS, Nakajima T. Anoplin, a novel antimicrobial peptide from the venom of the solitary wasp Anoplius samariensis. Biochim Biophys Acta. 2001 Nov 26;1550(1):70-80. doi: 10.1016/s0167-4838(01)00271-0. PMID: 11738089.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"