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Product Name
Human ANGPT4 (Fc Tag) recombinant protein
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Description
Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis.
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Protein name
Angiopoietin-4
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Protein short names
ANGIOPOIETIN-4; ANG-3; ANG4; ANG-4; AGP4; AGPT4; ANGIOPOIETIN 3; ANG3; DJ824F16.2 (ANGIOPOIETIN 4)
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Uniprot ID
Q9Y264
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Gene Name
ANGPT4; ANG3; ANG4
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human ANGPT4 (Q9Y264) C-terminal fragment (Met 282-Ile 503) was fused with the Fc region of human IgG1 at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human ANGPT4/Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 483 amino acids and has a calculated molecular mass of 53.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhANGPT4/Fc monomer is approximately 66 kDa due to the glycosylation.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human Angiopoietin 4 / ANG4 / ANGPT4 Protein (Fc Tag) SDS-PAGE
Related Products / Services
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