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  • angiopoietin-1 derived peptide

angiopoietin-1 derived peptide

Not For Human Use, Lab Use Only.

Cat.#: 319742

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* Buy 1 get 1 free (?) What is TFA?

Special Price 101.70 USD

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Product Information

  • Product Name
    angiopoietin-1 derived peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-QHREDG-OH
  • Sequence
    H-Gln-His-Arg-Glu-Asp-Gly-OH
  • Length (aa)
    6
  • Peptide Purity (HPLC)
    95.56%
  • Molecular Formula
    C28H44N12O12
  • Molecular Weight
    740.72
  • Source
    Synthetic
  • Form
    Powder
  • Description
    • QHREDG polypeptide is a peptide fragment derived from the growth factor Ang1(angiopoietin-1). It has shown potential in promoting cell survival and adhesion in various cell types.
    • This polypeptide can interact with integrin receptors, specifically β1-integrins, which play a crucial role in cell-extracellular matrix interactions. By binding to these receptors, QHREDG polypeptide may activate intracellular signaling pathways that lead to increased cell survival and adhesion. It has been demonstrated to enhance the survival of neonatal rat cardiomyocytes and endothelial cells, and may also have applications in promoting the survival and adhesion of other cell types.
    • Overall, QHREDG polypeptide holds promise as a tool for cell culture and tissue engineering applications, with the potential to improve cell viability and function.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Dang LT, Feric NT, Laschinger C, Chang WY, Zhang B, Wood GA, Stanford WL, Radisic M. Inhibition of apoptosis in human induced pluripotent stem cells during expansion in a defined culture using angiopoietin-1 derived peptide QHREDGS. Biomaterials. 2014 Sep;35(27):7786-99. doi: 10.1016/j.biomaterials.2014.05.018. Epub 2014 Jun 13. PMID: 24930852; PMCID: PMC4117357.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"