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Product Name
Human Actopaxin (GST Tag) recombinant protein
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Description
Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development (By similarity). Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishement of cell polarity, cell adhesion, cell spreading, and directed cell migration.
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Protein name
Alpha-parvin
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Protein short names
PARVIN; AU042898; ACTOPAXIN; CALPONIN-LIKE INTEGRIN-LINKED KINASE-BINDING PROTEIN; CH-ILKBP; ALPHA-PARVIN; 5430400F08RIK; 2010012A22RIK; AI225929; ACTP; MXRA2; MATRIX-REMODELING-ASSOCIATED PROTEIN 2; MNCB-0301
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Uniprot ID
Q9NVD7
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Gene Name
PARVA; MXRA2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human PARVA (Q9NVD7-1) (Met1-Glu372) was fused with the GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PARVA /GST chimera consists of 606 amino acids and has a predicted molecular mass of 69.4 kDa. It migrates as an approximately 69 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 60 % as determined by SDS-PAGE
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Validations
Human PARVA / Actopaxin Protein (GST Tag) SDS-PAGE
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