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Human Fetuin-A (His Tag) recombinant protein

Cat.#: 500151

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Product Information

  • Product Name
    Human Fetuin-A (His Tag) recombinant protein
  • Documents
  • Description
    Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.
  • Protein name
    Alpha-2-HS-glycoprotein
  • Protein short names
    AHSG]; A2HS; HSGA; AHSG; AHS; FETUA; FETUIN-A
  • Uniprot ID
    P02765
  • Gene Name
    AHSG; FETUA; PRO2743
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human Fetuin A (NP_001613.2) (Met 1-Val 367) precursor was expressed with a C-terminal polyhistidine tag.
  • Protein Species
    Human
  • Molecular weight
    The secreted recombinant human Fetuin A consists of 360 amino acids and predicts a molecular mass of 38.8 kDa. By SDS-PAGE under reducing conditions, rhFetuinA migrates as an approximately 55-60 kDa protein due to glycosylation.
  • Purity
    > 97 % as determined by SDS-PAGE
  • Activity
    1. Measured by its binding ability in a functional ELISA. Immobilized human FCN1 at 10 μg/ml can bind biotinylated recombinant human Fetuin-A with a linear range of 16-2000 ng/ml.
    2. Measured by its ability to inhibit active Cathepsin V cleavage of a fluorogenic peptide substrate Z-LR-AMC, R&D Systems, Catalog # ES008. The IC50 value is < 100 nM.
  • Validations

    Human Fetuin-A / AHSG / FETUA Protein (His Tag) SDS-PAGE

    Human Fetuin-A / AHSG / FETUA Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"