Allatostatin A-type IV.6 peptide
Not For Human Use, Lab Use Only.
Cat.#: 304927
Special Price 506.0 USD
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Product Name
Allatostatin A-type IV.6 peptide
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Documents
Batch to batch variation of the purity
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Sequence Shortening
NLKDDDLDQWQNDEEYSQFDDTEEDIEGREDDSQEIMDVD
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Sequence
Asn-Leu-Lys-Asp-Asp-Asp-Leu-Asp-Gln-Trp-Gln-Asn-Asp-Glu-Glu-Tyr-Ser-Gln-Phe-Asp-Asp-Thr-Glu-Glu-Asp-Ile-Glu-Gly-Arg-Glu-Asp-Asp-Ser-Gln-Glu-Ile-Met-Asp-Val-Asp
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Length (aa)
40
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Peptide Purity (HPLC)
97.2%
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Source
Synthetic
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Form
Powder
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Description
The source of Allatostatin A-type IV.6 is water flea (Daphnia pulex).
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Storage Guidelines
Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
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References
- Gard AL, Lenz PH, Shaw JR, Christie AE. Identification of putative peptide paracrines/hormones in the water flea Daphnia pulex (Crustacea; Branchiopoda; Cladocera) using transcriptomics and immunohistochemistry. Gen Comp Endocrinol. 2009;160(3):271-87.
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About TFA salt
Trifluoroacetic acid (TFA) has a significant impact on peptides due to its role in the peptide synthesis process.
TFA is essential for the protonation of peptides that lack basic amino acids such as Arginine (Arg), Histidine (His), and Lysine (Lys), or ones that have blocked N-termini. As a result, peptides often contain TFA salts in the final product.
TFA residues, when present in custom peptides, can cause unpredictable fluctuations in experimental data. At a nanomolar (nM) level, TFA can influence cell experiments, hindering cell growth at low concentrations (as low as 10 nM) and promoting it at higher doses (0.5–7.0 mM). It can also serve as an allosteric regulator on the GlyR of glycine receptors, thereby increasing receptor activity at lower glycine concentrations.
In an in vivo setting, TFA can trifluoroacetylate amino groups in proteins and phospholipids, inducing potentially unwanted antibody responses. Moreover, TFA can impact structure studies as it affects spectrum absorption.
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Molar Concentration Calculator
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Dilution Calculator
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Percent Concentration Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Related Products / Services
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"