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Product Name
ALKBH5 antibody
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Description
ALKBH5 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, HEK-293 cells, HepG2 cells. Observed molecular weight by Western-blot: 40-50 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ABH5 antibody; ALKBH5 antibody; FLJ20308 antibody; OFOXD antibody; OFOXD1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ALKBH5 recombinant protein (Accession Number: BC062339). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:107858(ALKBH5 antibody) at dilution of 1:400
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Background
ALKBH5, also named as ABH5 and OFOXD1, is a Dioxygenase that demethylates RNA by oxidative demethylation. It is a mammalian demethylase that oxidatively reverses m6A in mRNA in vitro and in vivo. ALKBH5 is required for spermatogenesis. There’re some isoforms of ALKBH5 with MW 40-44 kDa and 52 kDa.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"