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Product Name
ADIPOR2 antibody
- Documents
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Description
ADIPOR2 Rabbit Polyclonal antibody. Positive WB detected in L02 cells, HeLa cells, mouse uterus tissue. Positive IP detected in HeLa cells. Observed molecular weight by Western-blot: 44-50 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ACDCR2 antibody; adiponectin receptor 2 antibody; Adiponectin receptor protein 2 antibody; ADIPOR2 antibody; FLJ21432 antibody; PAQR2 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ADIPOR2 recombinant protein (Accession Number: XM_047429546). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
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Validations
L02 cells were subjected to SDS PAGE followed by western blot with Catalog No:107794(ADIPOR2 antibody) at dilution of 1:500
IP Result of anti-ADIPOR2 (IP:Catalog No:107794, 4ug; Detection:Catalog No:107794 1:500) with HeLa cells lysate 2800ug.
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Background
Adiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin (ADIPOR1 and ADIPOR2) have been identified. They mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. The human ADIPOR2 gene maps to chromosome 12p13.31, and encodes a 386-amino acid protein with a molecular weight of 44 kDa.
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References
- Ma H, You GP, Cui F. Effects of a low-fat diet on the hepatic expression of adiponectin and its receptors in rats with NAFLD. Annals of hepatology. 14(1):108-17. 2014.
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